What is a hypothesis? It is a suspended statement, whose validity (truth) has to be proved.
In order to prove this, you need first, a metaphysical frame. This metaphysical frame provides a logic that allows to establish whether the statement ‘fits’ inside and is thus true, or not.
Fundamentally, there are two: a priori one (demonstration through logic) and a posteriori or empirical one (demonstration through adequation to reality)
You have to put your statemente inside of the one or the other and then to define the field it belongs to: physics, chemistry, whatever
In order to have a field of science or other, you need the definition of principles, logic of interaction and main concepts definition.
After, you have to establish, if talking of empirical statements, the means by which you will obtain your validation, which usually are instruments used inside of variables (distortion angle caused by instruments towards reality) and ‘recurrence’: if what your hypothesis says occurs as often as possible inside of your ‘experiment’ you may say, it is ‘valid’ inside of a possible frame of exceptions, which should be defined, too.
Up to now it has been impossible to give foundation to the generalization or even universalization of statements out of empirical experimentation. If it is true to say « smoking may cause cancer » it seems impossible to say « smoking causes cancer » as the necessity in consequence, only possible inside of a logic of essences, can never be derived of empirical evidence and is, actually, only a priori.